Abstract
Biological system can adapt to dynamic environments by including both flexibility to environments and consistency as a whole system. What is the mechanism of such biological autonomy? In this paper, we try to clarify the mechanism by developing the adaptation model of Physarum, which consists of mechanical system in endoplasmic sol and chemical system in ectoplasmic gel. As the results, chemical-oscillator system in ectoplasm was shown to generate the information for spatial relationship in the whole system, and hydrodynamic system in endoplasm was shown to affect the chemical system on large time scale. Through chemo-mechanical coupling between these two systems, it was clarified that its temporal development has a character of hysteresis and that adaptation to dynamic environments is realized based on this process.