Systematic review of exhaled breath VOCs analysis and detection component for human diseases

Abstract

There are invasive and non-invasive diagnostic methods for diagnosing human diseases. Blood test and biopsies are examples of invasive diagnostic methods. On the other hand, non-invasive diagnostic methods include urinalysis and breath test. In recent years, disease diagnosis by breath test has attracted attention, and the use of breath test has been attracting attention especially for early detection of cancer. According to a recent study, more than 200 types of VOCs were detected in exhaled breath, and 28 types of VOCs were pointed out as marker substances for lung cancer.
Under these circumstances, research on breath tests has become a global trend for the purpose of leading to early detection of cancer.
In this study, recent literature was organized on the measurement method and the actual condition of exhaled breath components, focusing on VOCs in exhaled breath as a biomarker.