Abstract
In response to the growing health consciousness of smokers and the amended Health Promotion Law, which was fully enforced in April 2020, the number of users of heated tobacco products (HTPs) is increasing. Along with market expansion, competition for the development of HTPs has intensified, and the types of heating devices and their tobacco sticks have been increasing every year. HTPs reduce the amount of chemicals in mainstream smoke, but there is little evidence for health risks to active and passive smokers. The ISO (International Organization for Standardization) method and the HCI (Health Canada Intense) method are used as standard methods for chemical analysis of mainstream smoke generated from combustion cigarettes. For HTPs, CORESTA (the Cooperation Center for Scientific Research Relative to Tobacco) has published the technical report (Heated Tobacco Product-259-CORESTA technical report) for the collection of mainstream smoke in July 2020. This review outlines the characteristics and types of HTPs, puffing protocols for chemical analysis, and the biological effects of mainstream smoke generated from HTPs.
