Abstract
Heated tobacco product is a device which delivers nicotine into body by inhaling the mainstream aerosol generated during direct and/or indirect heating tobacco processes. The generated aerosol mainly consists of "water droplets", so that is different in physical and chemical property to conventional cigarette smoke. The novel media is being marketed as less hazardous than conventional cigarettes in Japan. However, the adverse health effects of inhaled and/or exposed aerosols should be further evaluated considering the difference in the physical and chemical property. Possible by-formation products should be also concerned because the novel tobacco employs the heating system of glycerin and propylene glycol to produce the water droplets. This paper reviewed the physical and chemical aspects of the mainstream aerosol of the heated tobacco products and discussed the formation of chemical components and behavior in indoor environment.
