The Journal of Silk Science and Technology of Japan
Online ISSN : 1881-1698
Print ISSN : 1880-8204
ISSN-L : 1880-8204
Development of Tissue Engineering Materials Based on Silk Fibroin –For Papers Written in Japanese–
Yasumoto NakazawaTetsuo Asakura
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2014 Volume 22 Pages 23-29


Silk fibroin from Bombyx mori silkworm has outstanding mechanical properties despite being spun from aqueous solution. Now, we have been developing several kinds of biomaterials, such as regeneration materials for bone, cornea and artificial blood vessel. In this paper, we present the applications of silk fibroins to tissue engineering. In the case of blood vessel regeneration, we have developed the small diameter vascular grafts made by silk fibroins. As results, the new grafts from silk fibroins have good patency, and these grafts were commonly covered with cells and platelets at 4 weeks after implantation.

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© 2014 by The Japanese Society of Silk Science and Technology
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