Abstract
To easily achieve desalting of a high-molecular-weight sericin (Virgin Sericin) solution on a large scale, we examined the use of a circulating dialysis system. Native-state sericin of high-molecular weight (cocoon shells of Sericin Hope) was dissolved in a lithium bromide aqueous solution, which was then subjected to circulating dialysis. The results indicated that circulating dialysis could be used to desalt Virgin Sericin solution on a large scale; the characteristics of the high-molecular weight sericin were maintained after the dialysis.