Abstract
Angiosarcoma frequently occurs on the scalp and face in elderly patients and tends to recur locally and metastasize early despite multimodality therapy. Generally, angiosarcomas have been treated with surgical excision, radiation therapy, chemotherapy and biotherapy. But the overall prognosis is poor. This report is a retrospective study of 260 patients with angiosarcoma, based on a study conducted by The Japanese Association of Dermatologic Surgery. We investigate prognostic factors and optimal treatment.
We consider that advanced age and formation of ulcers is associated with a poor prognosis. We suggest that surgical excision to histological negative margins and chemotherapy improve the prospect for survival.[Skin Cancer (Japan) 2009 ; 24 : 350-362]