Abstract
A 72-year-old man presented with erythematous plaques on his head and back, which had not responded to topical corticosteroids. Erythematous plaques were found on the parietal and occipital lesions of the head and on the back. A biopsy specimen from the occipital lesion showed extensive perifollicular and intrafollicular infiltrates of atypical lymphocytes and showed follicular mucinosis. Immunohistochemical stains of the atypical lymphocytes showed positive reaction for CD3 and CD4, and negative reaction for CD8 and CD20. Southern blotting demonstrated a clonal rearrangement of the T-cell receptor J-gamma chain. There was no abnormal lymph node swelling or visceral metastasis under positron-emission tomography and computed tomography. The patient was diagnosed with folliculotropic mycosis fungoides, stage IA. He was treated with topical PUVA and interferon gamma, which had little effect. Electron beam irradiation and oral etretinate were administered, and then the eruption regressed.[Skin Cancer (Japan) 2010 ; 25 : 145-149]
