Abstract
We report a case of mucinous carcinoma of the skin on the face. A 76-year-old man presented with a growing tumor in the left bucca which had begun four years earlier. On examination, a 22×24mm multilobular elastic hard tumor was present on the left cheek. This lesion showed capillary dilation on the surface, and a blister-like appearance in part. Under local anesthesia, the tumor was excised. Histological examination showed that the tumor was located in the dermis and subcutaneous fat with abundant mucin, which was separated by a fibrous septum. The mass of atypical tumor cells floated in the background of Alcian blue-positive mucin. Tumor cells displayed nuclear atypia and PAS staining positive cytoplasm. Immunohistochemically, tumor cells showed positive for EMA and CK7, slightly positive for CEA but negative for CK20. On gastro-intenstinal fiberscopy and CT scans of the body, we found no internal neoplasm. There is no evidence of recurrence or metastasis one year after the surgery.[Skin Cancer (Japan) 2010 ; 25 : 363-366]
