A case of Myxofibrosarcoma

Abstract

A 22-year-old man had noticed a subcutaneous mass on his right buttock for the past 6 years. He visited a local clinic where total excision was performed. Histological examination of the excised tumor revealed that atypical pleomorphic spindle cells had proliferated in the myxoidstoma. Immunohistochemical analysis of the specimen showed positive for vimentin as well as MIB-1 (index 5%). The tumor was diagnosed as myxofibrosarcoma. Subsequently, the patient visited our hospital for further treatment. We perfomed additional resection with a 5 cm margin and under the fascia. Neither recurrence nor metastasis has been found during the past 6 months.
It may sometimes be difficult to make a diagnosis for myxofibrosarcoma as low grade fibromyxoid sarcoma may have similar histological findings.
Therefore, we summarized different findings between two diseases, clinically and histologically.[Skin Cancer (Japan) 2012 ; 27 : 162-165]