Abstract
A 70-year-old man presented with a history of congenital prepubic sinus. He did not have it assessed, but recently he noticed the lesion had been increasing discharge. A histological examination revealed adenocarcinoma. Immunohistochemical findings showed that the tumor cells were positive for CEA and CK20, while they were partially positive for CK7. We suspected skin metastases from adenocarcinoma of the intestine, but there were no tumor cells. A whole body examination including PET revealed no evidence of lymphatic and visceral metastases. Based on these findings, we diagnosed this case as primary adenocarcinoma of the prepubis. We performed wide local resection and reconstruction using a vertical abdominis musculocutaneous (VRAM) flap. There is no dogma for the etiology of congenital prepubic sinus. Based on the postulate that it is a remnant of the cloaca, we can explain this case. This case is the first report of adenocarcinoma from congenital prepubic sinus.[Skin Cancer (Japan) 2013 ; 28 : 185-189]
