Abstract
A 39-year-old woman presented with a colored lump on her left knee that was causing pressure pain. The lump had first appeared 3 months earlier, and spontaneous pain that developed 2 weeks before admission led her to seek medical attention. On examination, there was a slightly raised, red, indurated area that measured 15 mm in diameter. This was diagnosed as an epithelioid hemangioendothelioma (EHE) after biopsy. The lesion was excised with a 20-mm margin and an all-layer dermoplasty was performed. Lymph node enlargement developed in the groin 2.5 months later, and computed tomography (CT) showed enlarged lymph nodes near the external iliac artery. A lymph node biopsy led to a diagnosis of metastasis. She was given five cycles of chemotherapy with adriamycin and ifosfamide. The patient remains in remission with no metastasis 47 months later. EHE in the skin is reported only rarely.[Skin Cancer (Japan) 2013 ; 28 : 329-335]
