Abstract
A 65-year-old woman presented with a several-year history of a slight red colored palpable indurated tumor on the right trunk. Skin biopsy examination revealed that the tumor cells had plump spindle-shaped cytoplasm, and the cells were arranged in fascicle or epithelioid nests with collagenous stroma. The inflammatory part showed a cellular infiltration that consisted of plasma cells and lymphocytes. The spindle cells were immune-reactive for smooth muscle actin and CD68, but they were negative for CD34, ALK and IgG4. According to these findings, the lesion was diagnosed as an inflammatory myofibroblastic tumor (IMT). IMT occurs in various organs and among them, the lung is the most frequently affected organ. Cutaneous IMT is very rare and to the best of our knowledge, only 18 cases of cutaneous IMT have been reported.[Skin Cancer (Japan) 2013 ; 28 : 325-328]
