Two cases of primary malignant melanoma of the esophagus

Abstract

Malignant melanoma of the esophagus is a relatively rare disease for which the prognosis is poor. Here, we reported two cases of primary malignant melanoma of the esophagus. Both patients had multiple lesions on the esophagus. They underwent surgical resection of the esophagus and regional lymph nodes. Chemotherapy using dacarbazine was used as an adjuvant therapy, but multiple metastatic lesions developed. We judged dacarbazine to be ineffective and switched to nivolumab for both patients. However, nivolumab was not effective, and both patients died within one year after surgery.[Skin Cancer (Japan) 2017 ; 32 : 6-11]