2019 Volume 33 Issue 3 Pages 179-184
We report two cases of mycosis fungoides (MFs).
Case 1 : A 66-year-old man was diagnosed with MF 40 years previously. At the age of 65 years, masses and ulcers appeared on his trunk, limbs, and eyelids. He was first treated with etretinate and narrow-band ultraviolet B phototherapy, which did not lead to any improvement.
Case 2 : A 66-year-old man was diagnosed with psoriasis 45 years previously. He was treated with corticosteroids, which maintained the symptoms well under control. However, he developed glaucoma, and the treatment was discontinued. Subsequently, the erythema on his trunk and face gradually spread, and tumors appeared.
We diagnosed both patients with MF (stage IIB) and treated them with low-dose oral etoposide and local electron beam radiation. This combination therapy markedly alleviated both the erythema and tumors within a few months. Although etoposide is a classical therapy, radiation in combination with etoposide is useful for the treatment of MF.[Skin Cancer (Japan) 2018 ; 33 : 179-184]
