2019 Volume 33 Issue 3 Pages 185-191
Case 1 : An 85-year-old woman presented with a tumor on her left knee that had appeared 5 months before, followed by many papules and nodules on her face and limbs. Histopathology and immunohistochemistry of the skin biopsy sample led to the diagnosis of blastic plasmacytoid dendritic cell neoplasm (BPDCN). Case 2 : A 91-year-old man presented with excessive purplish erythema on his trunk that had appeared 7 months before. Case 3 : A 67-year-old man presented with many papules and nodules on his limbs and trunk that had appeared a month before. These cases suggest that there are a variety of clinical features of BPDCN. We reviewed previous reports of BPDCN from the last 10 years. The clinical features of BPDCN can be divided into two types, namely, features associated with nodules and tumors and features associated with erythema and purpura. Cases with multiple nodules and tumors tend to be associated with poor prognosis.[Skin Cancer (Japan) 2018 ; 33 : 185-191]