2021 Volume 36 Issue 2 Pages 153-157
A 28－year－old woman with a history of Hashimoto’s disease visited us due to a rash with pain in the vulva. At the first consultation, erosive lesions, white wart－like plaques, and brown papules from the vaginal vestibule to the labia majora were observed. A diagnostic skin biopsy was performed, with the specimen including all of the above sites. Histopathological findings revealed atypical keratinocytes, fission images, and clumping cells in the entire epidermis in the erosive lesions and white wart－like plaques ; brown papules showed similar but slightly atypical findings. Epidermal cells were diffusely positive including the cytoplasm at both sites in almost all layers. The above findings were suggestive of Bowen’s disease and bowenoid papulosis of the vulva in the young woman. Lesion excision with a 5－mm margin was performed for treating the patient.[Skin Cancer (Japan) 2021 ; 36 : 153－157]
