Abstract
We report two cases with Squamous Cell Carcinoma (SCC) in situ caused by irradiation to hand eczemas, resisitant to any topical therapies.
Both of our cases clinically show palmer sclerosis and flexor restriction of the fingers, compatible to chronic radiation dermatitis. Although SCC arising in chronic radiation dermatitis is usually developed ten to twenty years after irradiation, in our cases SCC were found more than forty years after irradiation.