Abstract
We report a case of verrucous carcinoma of the glans penis. A 71-year-old man visited our hospital because of erythematous slightly infiltrated plaque on the glans penis. Histopathology disclosed that he had erythroplasia of Queyrat and the lesion was resected with 5mm margin. Three years later, he noticed 8mm×5mm-sized verrucous nodule on the excised area. Histopathology showed marked hyperkeratosis, irregular acanthosis and individual keratinization, but minimal cellular atypia. Immunohistochemical analysis for HPV was negative. He was treated by wide excision with skin graft, and no evidence for recurrence or metastasis has been detected so far. [Skin Cancer (Japan) 2001; 16 :124-127]
