Abstract
We reported a 61-year old male patient with a huge solid tumor, which surface was reddish and granular, on his right axilla. The tumor had rapidly grown during one month.
Histologically, nest of tumor cells was observed in dermis to subcutaneous tissue, and tumor cells had eosinophilic cytoplasm and atypical nuclei. Immunohisto-chemical examination showed that tumor cells were positive for cytokeratin, PAS (with diastase-resistance), and GCDFP-15, but not for vimentin and S-100 protein. A diagnosis of poor-differentiated sweat gland carcinoma was made.
MRI examination revealed that the tumor extended to around right apical nodes. No obvious metastatic lesion was detected.
In treatment, the selective intraarterial administration of cisplatin and systemic administration of adriamycin were combined with local X-ray irradiation. These combination therapy led to remarkable clinical resolution. [Skin Cancer (Japan) 2001; 16: 120-123]
