Abstract
We reported a case of Muir-Torre Syndrome. A 67-year-old man revisited our clinic complaining of two small nodules on his nose. Histological examination revealed sebaceomas. He had two keratoacanthomas at his first visit 18 years ago. Altogether, he had 4 keratoacanthomas, 2 squamous cell carcinomas, 4 sebaceous tumors, 2 benign skin tumors and two colorectal carcinomas during his entire course. The histology of the squamous cell carcinomas was deep invasive and prominent keratosis and its prognosis was good. This case suggested that multiple keratoacanthomas was the possibility of the initial sign of Muir-Torre syndrome. We discussed on the prognosis of squamous cell carcinoma of MuirTorre Syndrome. [Skin Cancer (Japan) 2003; 18: 189-192]
