Abstract
A 58-year-old female came to our hospital with a tumor on her scalp with 30 years' history. The tumor gradually enlarged and had secreted mucous discharge for several years. Histologically, it showed poroma cells with proliferating small basophilic cells, scattered sweat ducts, and atypical clear cell proliferation. Immunohistologically, endothelial cells of eccrine ducts and atypical cells showed positive stain in PAS, CAM5.2, EMA, and negative in CEA. This suggested a malignant change of eccrine poroma to eccrine porocarcinoma. [Skin Cancer (Japan) 2004; 19: 322-325]