Abstract
Three patients with cutaneous malignant melanoma metastatic to the liver were treated in our institute, two with hepatic chemoembolization using cisplatin and gelatin sponge, and one with hepatic trans-arterial infusion using cisplatin only. Complete response was observed in one patient who survived without recurrence for 62 months. The patient with stable disease survived for 22 months ; the patient with progressive disease survived for 9 months but both died with tumor progression. In general, melanoma is fatal for patients with liver metastasis. The median survival time was estimated at only 4-7 months. We considered this therapy adequate therapy for melanoma patients with liver metastasis, for a prolonged survival time with less treatment related morbidity. [Skin Cancer (Japan) 2005; 20: 70-74]
