Abstract
Ray amputation of the left little finger was performed on a 70-year-old woman due to cutaneous malignant melanoma (Stage IA). No recurrence or metastasis was found during a 10-year follow-up after the surgery. Twenty-four years after the surgery, massive subcutaneous and distant lymph node metastases were found. Liver and lung metastases were also progressive. DTIC, ACNU, CDDP, and Tamoxifen (known as DAC-Tam regimen) were used for systemic chemotherapy. The liver metastasis was treated with intra-arterial CDDP and beta-interferon injection combined with TAE. After three courses of the chemotherapy, lymph node and subcutaneous metastases had decreased, but the liver metastasis showed no change. She died of brain metastasis one year after the first detection of the metastases. [Skin Cancer (Japan) 2006; 21: 41-44]
