Abstract
We report a case of rapidly aggressive eccrine porocarcinoma. A 51-year-old man presented with a partially ulcerated giant tumor on the scalp. Although he had noticed a small tumor from his adolescence, it rapidly grew larger in these three months. Despite surgical resection, including underlying cranial bone, cervical lymph nodes became involved within one month. Lymph nodal dissection and local radiotherapy were performed, but the tumor recurred at the neighboring skin and lymph nodes. In spite of systemic chemotherapy and local irradiation, the skin lesion spread to the anterior chest and upper abdomen, and the patient died of pulmonary failure. [Skin Cancer (Japan) 2006; 21: 340-344]