Abstract
Case 1: A 73-year-old woman presented with vaginal malignant melanoma. She underwent surgical procedures and three courses of chemotherapy (DAV-Feron) from September 30. Case 2: A 49-year-old woman presented with vulvar malignant melanoma. She was hospitalized at our department, and one course of DAV-Feron treatment was given on December 15. Her condition, however, showed no improvement and she died on March 15, 2006. Of all malignant melanomas, those arising primarily in the female genital organ are relatively rare and their detection is often delayed because of their anatomical features, the patients' sense of embarrassment, etc. Their standard treatment is based on the same therapy as that used for malignant skin melanomas. However, progressive melanomas are intractable with a poor prognosis. Therefore, through accumulating more data on similar cases, a further advance in their treatment is called for. [Skin Cancer (Japan) 2006; 21: 368-371]
