Abstract
We present a case of non-pigmenting fixed drug eruption. A 28-year-old woman was treated with a single dose of intravenous clindamycin and betamethasone in July 2009. Several days later, itchy erythematous eruptions developed on her neck, left upper arm, lower back and left thigh. The lesions faded within several days without residual pigmentation. In September 2010, she again developed similar erythematous eruptions at the same sites following treatment with a single dose of intravenous clindamycin and betamethasone. Intravenous provocation tests with clindamycin induced erythematous eruptions at the same sites. A closed patch test with clindamycin was positive. On the basis of these findings, we diagnosed her with non-pigmenting fixed drug eruption caused by clindamycin. Drug eruption caused by clindamycin is rare. We found 50 cases of non-pigmenting fixed drug eruption in the literature and this is the first case caused by clindamycin. Skin Research, 11: 403-408, 2012
