Abstract
A 42-year-old woman presented with a pruritus, linear rash over the the left abdomen. One month prior to the appearance of the skin lesions, the patient had eaten raw Salangichthys microdon from Aomori prefecture. Because of its prevalence in Aomori, creeping disease due to Gnathostoma nipponicum was suspected. She was treated with oral ivermectin, which relieved her symptoms. However, the eruption reappeared one month later and she received ivermectin again with a good therapeutic effect. Since measurement of antibody titer to Gnathostoma nipponicum is not available, we used antibody titer to Gnathostoma doloresi, which shares antigenicity with Gnathostoma nipponicum. During the course of treatment, the antibody titer to Gnathostoma doloresi decreased gradually. It is suggested that the cross-reactivity between the two species is useful for the monitoring of Gnathostoma nipponicum.Skin Research, 12: 122-125, 2013
