Abstract
A 65-year-old female patient had noticed an itchy mass in the vulva two months previously. We noted an elastic-hard, 1cm-diameter mass accompanied by superficial erosion on the clitoris, as well as shiny white spots on the inner side of the left and right labia majora. On the basis of biopsy findings, she was diagnosed with squamous cell carcinoma with lichen sclerosus et atrophicus. We performed resection 1cm distant from the affected site. Clinicopathologically, squamous cell carcinoma in the vulva is classified into three types: warty and basaloid types involving perimenopausal development through human papilloma virus infection, and the keratinizing type observed commonly in elderly people and suggested to originate from lichen sclerosus et atrophicus. Patients with the keratinizing type of this disease generally show a poor prognosis and may require careful follow-up.Skin Research, 12: 88-91, 2013
