Hifu no kagaku
Online ISSN : 1883-9614
Print ISSN : 1347-1813
ISSN-L : 1347-1813
CASE REPORT
A Case of Pseudoxanthoma Elasticum Accidentally Diagnosed with a Biopsy Specimen of Extramammary Paget's Disease
Kohei YAMAUCHINaoki OISOTomohiko NARITAAkira KAWADA
Author information
JOURNAL RESTRICTED ACCESS

2014 Volume 13 Issue 6 Pages 421-425

Details
Abstract
A 71-year-old man was referred to us because of erythema with erosions and nodules on the genital area. It had gradually enlarged over several years. Physical examination revealed an asymptomatic erythematous plaque with erosions and nodules, 200×100mm in size, on the genital area. A biopsy specimen showed not only large round cells with ample pale-stained cytoplasm in the epidermis and mononuclear inflammatory cell infiltration in the upper dermis, but also elastorrhexis in the middle to lower dermis. With Elastic van Gieson stain and von Kossa stain, we confirmed marked degeneration of elastic fibers with calcium deposition. Physical reexamination revealed asymptomatic pale-yellowish papules, 1 to 3mm in diameter, on the lateral neck, groin, and proximal femur. We diagnosed the erythematous plaque on the groin with extramammary Paget's disease as pseudoxanthoma elasticum. Our case reemphasizes the importance of complete clinical and histopathologic assessment as extramammary Paget's disease and other skin disorders including pseudoxanthoma elasticum may occasionally be identified in elderly patients.Skin Research, 13: 421-425, 2014
Content from these authors
© 2014 Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association
Previous article Next article
feedback
Top