Abstract
A woman in her 30s visited a previous hospital for a subcutaneous tumor in the right lower abdomen that had grown over the past year. As malignancy was suspected, she was referred to our hospital for treatment. The tumor was surgically removed. Histopathologically, the tumor was well-circumscribed and exhibited proliferation of spindle-shaped tumor cells, which were arranged in fascicles. Proliferation of the tumor cells was seen in some areas of edematous stroma. There were numerous small to medium-sized vessels and collagen fibers. Immunohistochemically, the tumor cells were positive for CD34, progesterone receptor and estrogen receptor, and negative for SMA and desmin. We diagnosed this tumor as cellular angiofibroma based on the histological features and immunohistochemistry. Cellular angiofibroma is a rare mesenchymal tumor of the vulva or perineal region. We report a case of cellular angiofibroma of the lower abdomen and review the relevant literature.Skin Research, 17: 157-162, 2018
