Abstract
Here we report severely burned two cases with alcoholic liver disease. Their transaminases were remarkably elevated with suppressed choline esterase levels. Because of the widely distributed third degree burn, we have to perform debridement followed by thin split skin grafts for several times. It happened bleeding at the first operation in both cases. Coagulatory insufficiency developed because of the consumption of factor VII and XIII by burn with poor supply of them by severe alcoholic liver dysfunction. Then, we pretreated them with fresh frozen plasma and vitamin K, and surgically treated them after returning the clotting factor within normal level. Since the alcoholism patients are the high risk group for the severe burn, we should be careful to keep coagulatory function within normal levels for these patients.
