Abstract
A 37 year old woman was consulted to our hospital for the evaluation of many brown or black flat tumors on the trunk on October 1st, 1997. According to the patient, some of them had became flared with mild tenderness and their color changed to reddish black. Since the first visit , tumors began to become smaller and changed to small prominent nodules, and then gradually fell off in eight months. Histology of the nodule without inflammation was consisted with seborrheic keratosis. The histology of inflamed tumors exhibited that both edges of the horny layer invaded into the epidermis. The small prominent nodules that just began to fall off showed the papillomatous change of the epidermis accompanying hematoma in the horny layer and infiltration of plasma cells, eosinophiles and lymphocytes.
According to Berman, spontaneous regression of seborrheic keratosis includes three types, 1) papillomatous changes of the picked epidermis, 2) pseudo-horny cyst going through the epidermis and 3) infiltration of inflammatory mononuclear cells in the upper dermis. Taken together of our findings, the regression pattern of seborrheic keratosis in our case is consisted with the type of the papillomatous changes of the picked epidermis in the classification by Berman.
