Abstract
We here describe two cases of non-pigmented basal cell epitheliomas. Case 1, the patient was a 57-year-old woman. She noticed a flesh colored nodule on her dorsum nasi for 5 years ago. In April 2000, she visited to our department because of examining this tumor. The histopathological examiniation revealed a solid type basal cell epithelioma. Case 2, the patient was a 36-year-old man. He noticed a flesh colored nodule on his saddle nose for 15 years ago.
In Novmber 1999, he visited to our department because of examining this tumor. The histopathological examiniation revealed a basal cell epithelioma which was composed of solid lesions and morphea-like lesions. The immunohistochemical studies of our cases showed basal cell epithelioma patterns using antibodies to human membrane epithelioma antigen(EMA), human cytokeratin 20, NSE, human bcl-2 oncoprotein and CD34 ; The human bcl-2 oncoproteins are positive of our cases, but other antigens are negative.
We analized 12 cases of non-pigmented basal cell epitheliomas that have been reported for 10 years ago in Japan. And we concluded that non-pigmented basal cell epitheliomas in the Japanese patients can be classified intofive clinical types.
