2021 Volume 20 Issue 3 Pages 208-211
A 17-year-old woman, who was an active member of a cheerleading club since last year, developed edema and erythema on both lower legs accompanied by a burning sensation, which worsened during exercise such as club activities. At the first visit, poorly demarcated diffuse erythema was found symmetrically on both lower legs. We diagnosed her with cutaneous erythromelalgia based on the clinical course and skin findings. Neither acetaminophen nor aspirin was effective, but her symptoms and pain improved after taking pregabalin even during club activities. She still felt pain after a bath, which disappeared by increasing the dose of pregabalin. She is now able to live a normal daily life. Exercise and thermal stimulation were considered the inducing factors in this case, and pregabalin was effective in suppressing the symptoms while continuing club activities. Although there is no established treatment for cutaneous erythromelalgia, pregabalin was reported to be beneficial in previous cases and may be considered as a treatment option. Skin Research, 20 : 208-211, 2021
