Abstract
We report a case of multiple Bowen’s disease due to arsenic intake. The patient was a 81-year-old female. She had had arsenic intake for a skin lightening beauty treatment for 1 year in 1944. The number of erythematous plaques had increased since about 1990, when she recognized the painful erythematous plaque on the light of her flank. She visited our hospital complaining of the plaques on August 1, 2001. We surgically resected her 30 plaques. The histopathological examination of plaques showed Bowen’s disease. Of 13 cases reviewed, the latent interval is 39 years, on the average, from the taking of arsenic chemical to the evidence of multiple Bowen’s disease.
