Abstract
A 70-year-old man showed recurrent bilateral flaring subcutaneous induration around the ears since Feb, 2006. A CT scan showed the bilateral parotid glands swelling, laboratory data revealed high levels of sIL-2 receptor and salivary amylase. A skin biopsied specimen from the induration lesion showed noncaseating granuloma throughout the dermis to fat tissue. Aangiotensin converting enzyme (ACE) was normal range and other symptoms associated with lung, heart, eyes were not shown. We diagnosed this case as Mikulicz disease with sarcoid reaction. Subcutaneous induration spontaneously regressed without medication. In some diseases showed bilateral salivary gland swelling, Mikulicz disease and Mikulicz syndrome were very rare cases. We briefly discussed histories of Mikulicz syndrome and Mikulicz disease and new finding about Mikulicz disease.
