Abstract
A 62-year-old man developed sclerotic and glossy skin mainly on the extremities, and the partial abdomen and lumbar regions. Limited digital, elbow and knee joint movement, and hair loss on bilateral lower legs, axilla and head were associated. Laboratory data showed eosinophilia, hyper-gammaglobulinemia, positive antinuclear antibody, and increased soluble interleukin-2 receptor (sIL-2R). Histopathologically, infiltration of eosinophils to fascia and hypertrophy of fascia were observed. We diagnosed eosinophilic fasciitis and administered prednisolone. Although hair loss in patients with systemic scleroderma has been reported, systemic hair loss with eosinophilic fasciitis is unusual. The pathomechanism of hair loss is discussed.
