Abstract
We report a case of median raphe cyst of the penis. A 37-year-old man had had a penile subcutaneous tumor for 20 years, which had been slowly increasing in size. We resected the tumor under local anesthesia. Histopathologically there were two cysts in the dermis. The cyst wall consisted of stratified squamous epithelium and cuboidal epithelium. We diagnosed this case as a median raphe cyst of the penis based on these clinical findings and histopathological findings. Although the etiology of the tumor remains unknown, we think that a secondary factor was involved in the formation of median raphe cyst of the penis because the tumor, which has been left for a long time in our case, began to increase in size during the course. Parameatal cyst is another disease which causes a penile cyst; however, parameatal cyst could differ from median raphe cyst because there have been few reports of a cyst wall consisting of squamous epithelium in parameatal cyst, whereas the cyst wall consists of squamous and cuboidal epithelium in median raphe cyst. Further study is needed to differentiate these two diseases.
