Skin research
Online ISSN : 1884-541X
Print ISSN : 0018-1390
ISSN-L : 0018-1390
Two Cases of Necrobiosis Lipoidica
Hideki ENDOKazuko SUGIHARAYuri SAKAMOTOKen FUKUIYoshinori ARAGANEHidekazu YAMADATadashi TEZUKA
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JOURNAL FREE ACCESS

1998 Volume 40 Issue 5 Pages 484-487

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Abstract
The first case was a 62-year-old woman who noticed sharp but irregular demarcated patches with erythema on both lower legs since the age of 57. As these lesions continued to increase in size, she visited our out-patient clinic on Feb.4, 1998. Skin biopsy revealed granulomatous change with disrupted collagen fibers in the dermis. She also had diabetes mellitus. The second case was a 60-year-old woman with progressive and erythematous, atrophic lesions on both lower legs. Biopsy specimen showed degenerative change in collagen fibers, surrounded by histiocytes and giant cells. She did not have diabetes mellitus.
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© Meeting of Osaka Dermatological Association
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