Abstract
In the previous paper, we clarified the defects which the conventional methods of a fluidized bed granulation possessed and found the conditions to reduce these defects. In this paper, we compared the growth of a particle and the mechanism of compactness and smoothness in the conventional method with those of new method and found the conditions to improve the compactness and smoothness of granules in both methods. This accounted for the difference in these methods.
In conventional methods, the compactness and smoothness of granules occurred remarkably in the region of above 300-400μm particle size on regard to the relationship between granulating time and the growth of the particle. They slowly occurred in the region of under 300-400μm in particle size. It was guessed that this was because the plastic deformation of granules was proceeded by contact with the particle-die wall and particle-particle when the gravity of granules exceeded a limit.
On the other hand, in new method the compactness and smoothness of granules occurred as soon as the agitating started regardless of the feed rate of spraying solution. It was supposed that the compactness and smoothness were attained regardless of granule size as the plastic deformation of granules the compulsively occurred by means of mechanical agitating in new method.
