Abstract
The effect of the water contet and crystallinity of heptakis-(2, 6-di-O-methyl)-β-cyclodextrin (DM β CD) on the physicochemical properties of a sealed heated compound with naphthalene was investigated using powder X-ray diffractometry, thermal analysis and solid state fluorescence spectroscopy. The water content in amorphous DM β CD affected the inclusion formation of stable and metastable inclusion compounds, even if it had little influence on the inclusion molar ratio. A suitable amount of water (1%-4%) caused metastable inclusion formation between DM β CD and naphthalene. After the sealed heating of crystalline DM β CD and naphthalene, only stable inclusion compound was obtained. It was found that amorphous DM β CD containing a small amount of water could form a 1:2 inclusion compound with naphthalene.
