推算モデルによる床用敷物含有化学物質の消費者暴露特性評価とその設定パラメータに関する考察

抄録

In this study, to comprehend consumer exposure characteristics of DMF (N,N-Dimethylformamide) and 2E1H (2-Ethyl-1-hexanol) emitted from EVA (Ethylene-vinylacetate) resin mats, we applied prediction models of TRA, ConsExpo, IH MOD/SkinPerm to their inhalation and dermal exposure. Weight fraction of target substances in products are very important for exposure estimation but mostly unknown. We assumed to set 0.1–1% to them and verified the adequacy by experimental emission rate and model fitting. Exposure predictions suggested that setting new EVA resin mats has initially major impacts to indoor air environment. Dermal exposure was not also negligible as exposure route. ConsExpo would not be applicable to substances having high dermal deposition rate and low K_ow (Octanol/water partition coefficient) by only selecting default values of layer thickness. It would be necessary to modify its dermal prediction equation. Mass transfer coefficient was not a sensitive parameter for ConsExpo. Sparks method increased only 20–32% of mean event concentration as compared to flat plate method.