Cambodia is the constitutional monarchy nation located in the Indo-China peninsula which shares the east common border with Vietnam, the west border with Thailand, the north border with .Laos, and the south border with the South China Sea. The major industries of Cambodia are tourist business and manufacturing business including sewn products and shoemaking as well as the primary industry. As Cambodia attracts lots of attention as one of the countries for risk diversification of China +1 in recent years, investments from foreign countries are increased and economic development is shown though it is a least developed country. Today, China and South Korea are expanding their business positively in Cambodia to make a large sum of overseas investments on the society’s infrastructures and the real estates. On the other hand, Cambodia adopts the industrial policy of utilizing positive investments by the foreign capitals. The approach on an industrial cluster is seen on the industrial accumulation ground in the domestic special economic zone. In this text, we will examine the possibility of the industrial cluster formation in Cambodia with the major comparison of cases with two special economic zones in Phnom Penh and the Sihanoukville port.