Treatment of EEG Abnormalities in Benign Childhood Epilepsy with Centrotemporal Spikes

抄録

Benign childhood epilepsy with centrotemporal spikes (BECTS) is the most common childhood type of epilepsy. Whether treatment should be initiated and the necessity of treatment for abnormality of interictal encephalography (EEG) in BECTS remain controversial. We investigated the relationship between age in months at seizure onset, duration of interictal EEG abnormality, and the period until the disappearance of seizures in BECTS patients receiving in treatment (TR group) or no-treatment (NT group). There was a negative correlation between the age at seizure onset and the duration of interictal EEG abnormality (p<0.01), whereas there was a positive correlation between the duration of interictal EEG abnormality and the period until the disappearance of seizures (p<0.05). There was a significant difference in the duration of interictal EEG abnormalities and the period until the disappearance of seizures between the NT and TR groups (p<0.01). Our results suggested that there may be an association between interictal EEG abnormalities and the duration of seizure in BECTS, indicating that interictal EEG abnormality may be a target for treatment.