2022 年 13 巻 1 号 p. 23-28
The purpose of this study was to investigate histological findings at the puncture site on the pancreatic surface by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) and to consider the potential and clinicopathological significances for microscopic needle tract seeding (NTS) on the pancreatic side. We evaluated 21 cases of pancreatic body or tail cancer for which both EUS-FNA and surgical resection had been performed. A single bleeding spot with shrinkage on the pancreatic anterior surface near the targeted tumor was regarded as the puncture site. The majority of cases showed flat shape and granulation tissue formation. Cancer cell clusters were present in 10 cases (48%), of which 7 cases were considered to potentially have microscopic NTS. There were no significant differences in clinicopathological and prognostic factors between the 7 NTS-positive and 14 NTS-negative cases. This study showed that microscopic NTS on the pancreatic side is not uncommon, although it may not indicate a significant increased risk of local recurrence or dissemination that directly affects the prognosis of patients.
