Study of hepatitis B virus infection and its prevention in dental students
1989 Volume 38 Issue 4 Pages 968-973
Details
1989 Volume 38 Issue 4 Pages 968-973
HB virus associated antigen-antibody in dental students as examined in order to find out of HB virus infections occurring.
In order to prevent HB virus infections, the students were inoculated with HB vaccine only if they had previously showed negative HBs antibodies before their clinical training.
1. Among 581 dental students, 6 (1.0%) showed positive HBs antigen, and 27 (4.6%) showed positive antibody. The total cases of HB virus infection, which were positive with HBs antigen and/or and HBs, were 33 (5.7%).
2. During the past 4 years, 506 dental students had clinical dental training. In that period, one student changed to HBs antigen positive, two changed to and HBs positive and 6 changed to and HBc positive. Consequently, 6 students were infected with HB virus. However, these 6 students showed transient and latent infections with no jaundice or other clinical symptoms.
3. Seventy-five students had been inoculated with HB vaccine 3 times. Fifty-nine students (78.7%) showed anti HBs positive. Those who were still negative anti HBs had inoculations a 4 th and 5 th time. Consequently the and HBs positive students increased to 85.3% after the 4 th time, and 89.3% after the 5 th time. The results showed that additional inoculations were effective.
4. Each company's human plasma derived HB vaccine showed different values or effectiveness of and HBs acquisition.
5. After 3 inoculations, the rates of and HBs were 75.0%(45/60) in males, and 93.3%(14/15) in females. Also females had a high titre of and HBs.
