1995 Volume 44 Issue 3 Pages 450-454
W e experienced a case of secondary syphilis in a 31-year-old male with eruption of the oral mucosa. Defined grayish white surfaced erosion with raised margin was observed on the lower lip. Slightly raised grayish white lesion was observed on the apex and bilateral edges of tongue, and a well-defined grayish white lesion with redness on the palate was also observed. The serological tests for syphilis were positive, and Treponema pallidum could be stained by Warthin-Starry method and immunofluorescene technique in the biopsy specimen taken from the lower lip and tongue. After the treatment with AMPC 1.5g/day for 8 weeks, and PCV 1.2 million unit/day for 4 weeks, the oral lesion disappeared in 3 weeks.