Effect of DPPD and Ethoxyquin on the Muscular Dystrophy of Carp Induced by Oxidized Saury Oil

Abstract

It was previously observed that the synthetic antioxidants, methylene blue, BHA and ethyl gallate, are all ineffective on muscular dystrophy of carp induced by oxidized saury oil and that methylene blue promotes the disease.
Succeeding to the previous work, the effect of DPPD and ethoxyquin was compared with that of DL-α-tocopheryl acetate on the muscular dystrophy of carp and that of methylene blue was reexamined.
As shown in Table 3, the both antioxidants, DPPD and ethoxyquin did not counteract the action of oxidized saury oil and the former killed carp in 30-40 days at the level of 250mg%. When kept on a diet containing 120mg% of methylene blue, carp showed a typical sign of the disorder in 7 days and the rate of diseased fish exceeded 90 percent in 20 days. A high blood glucose level was observed in the lots, in which fish showed a high percentage of muscular dystrophy.