Calcitonin-like Immunoreactivity in the Brockmann Bodies of the Medaka (Teleostei)

Abstract

In the Brockmann bodies of the Medaka Oryzias latipes (Teleostei) calcitonin-like immunore-activity was detected immunohistochemically. Many cells in the endocrine tissue of the Brockmann body were stained positively by anti-salmon calcitonin antiserum and anti-eel calcitonin antiserum. Administration of the Brockmann body homogenate to rats caused significant hypocalcemia and hypophosphatemia. However, the calcemic potency of a Brockmann body was rather lower than that of the ultimobranchial gland of the Medaka itself.